New York, September 8 (IANS) Scientists have found that high blood pressure may lead to bone problems and bone damage related to osteoporosis. In laboratory studies in rodents, they found that, compared to young mice without hypertension, young mice with provoked hypertension had a large 24 percent decrease in bone volume share.
They also experienced an 18 percent reduction in wipe thickness such as trabecular bone situated toward the ends of long bones, such as the femurs and spine, and a 34 percent reduction in assessed deformation force, which it is the capacity of the problems that remain to be solved. various kinds of power be drawn.
“By contrast, more established mice given angiotensin-II implantation did not show comparative bone misfortune. Hypertension and osteoporosis are normal diseases that affect people, and some may have both all the time.
“The bone marrow is where both new bone and invulnerable new cells are created. We suspect that what is most favorable to fire-resistant cells in the bone marrow may be causing bone damage and making it more vulnerable,” said Elizabeth Maria Hennen of Vanderbilt University in Nashville, Tennessee, USA.
“By understanding how high blood pressure adds to osteoporosis, we may have the option to reduce the risk of osteoporosis and better protect people in the future from having finer breaks and lower personal satisfaction,” he added.
The researchers analyzed young mice (matched human age 20-30 years) with activated hypertension to more established mice (matched human age 47-56 years) without hypertension to understand the relationship between hypertension and bone maturation, according to the study published in the Meeting of the Scientific Sessions on Hypertension 2022 of the American Heart Association.
“Twelve young rodents and 11 more established rodents received angiotensin II, a chemical that causes high blood pressure for a long time,” the specialists said.
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“Two other control groups of 13 young mice and 9 old mice obtained supportive agreement that excluded angiotensin II, and these mice did not promote hypertension,” they added.
After a month and a half, the bones of the rodents in each of the four groups were broken down using miniature figure tomography, a high-level imaging method.